PK/PD modeling and simulation of the in vitro activity of the combinations of isavuconazole with echinocandins against Candida auris

Abstract In vitro combination of echinocandins and isavuconazole against the emerging species Candida auris is mainly synergistic. However, this combination has not been evaluated in clinical settings. A pharmacokinetic/pharmacodynamic modeling and simulation approach based on in vitro data may be h...

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Bibliographic Details
Main Authors: Unai Caballero (Author), Elena Eraso (Author), Guillermo Quindós (Author), Valvanera Vozmediano (Author), Stephan Schmidt (Author), Nerea Jauregizar (Author)
Format: Book
Published: Wiley, 2023-06-01T00:00:00Z.
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