The Extracellular Matrix Enriched With Exosomes for the Treatment on Pulmonary Fibrosis in Mice

• Главные авторы: Yanzhen Yu (Автор), Xingzhi Liu (Автор), Zhe Zhao (Автор), Zhongjuan Xu (Автор), Yong Qiao (Автор), Yuanshuai Zhou (Автор), Hong Qiao (Автор), Junjie Zhong (Автор), Jianwu Dai (Автор), Guangli Suo (Автор)
• Формат: ‌
• Опубликовано: Frontiers Media S.A., 2021-12-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

Pulmonary fibrosis (PF) is a severe respiratory disease caused by lung microenvironment changes. TGF-β/Smad3 signaling pathway plays a critical role in the fibrotic process. MicroRNA-29 (miR-29) has proved to alleviate the occurrence of PF by downregulating TGF-β/Smad3 signaling pathway. The miRNA a...