The Extracellular Matrix Enriched With Exosomes for the Treatment on Pulmonary Fibrosis in Mice

• Hlavní autoři: Yanzhen Yu (Autor), Xingzhi Liu (Autor), Zhe Zhao (Autor), Zhongjuan Xu (Autor), Yong Qiao (Autor), Yuanshuai Zhou (Autor), Hong Qiao (Autor), Junjie Zhong (Autor), Jianwu Dai (Autor), Guangli Suo (Autor)
• Médium: Kniha
• Vydáno: Frontiers Media S.A., 2021-12-01T00:00:00Z.
• Témata: article
• On-line přístup: Connect to this object online.

Pulmonary fibrosis (PF) is a severe respiratory disease caused by lung microenvironment changes. TGF-β/Smad3 signaling pathway plays a critical role in the fibrotic process. MicroRNA-29 (miR-29) has proved to alleviate the occurrence of PF by downregulating TGF-β/Smad3 signaling pathway. The miRNA a...