The Extracellular Matrix Enriched With Exosomes for the Treatment on Pulmonary Fibrosis in Mice

• Main Authors: Yanzhen Yu (Author), Xingzhi Liu (Author), Zhe Zhao (Author), Zhongjuan Xu (Author), Yong Qiao (Author), Yuanshuai Zhou (Author), Hong Qiao (Author), Junjie Zhong (Author), Jianwu Dai (Author), Guangli Suo (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Pulmonary fibrosis (PF) is a severe respiratory disease caused by lung microenvironment changes. TGF-β/Smad3 signaling pathway plays a critical role in the fibrotic process. MicroRNA-29 (miR-29) has proved to alleviate the occurrence of PF by downregulating TGF-β/Smad3 signaling pathway. The miRNA a...