Mangiferin Relieves Lipopolysaccharide-Induced Injury by Up-Regulating miR-181a via Targeting PTEN in ATDC5 Cells

• Hauptverfasser: Yunfei Ma (Verfasst von), Ying Liu (Verfasst von), Yunyan Ma (Verfasst von), Nan Jiang (Verfasst von), Lei Wang (Verfasst von), Bowei Wang (Verfasst von), Wanting Niu (Verfasst von), Yanjun Hu (Verfasst von), Qingrong Lin (Verfasst von), Bin Yu (Verfasst von)
• Format: Buch
• Veröffentlicht: Frontiers Media S.A., 2020-03-01T00:00:00Z.
• Schlagworte: article
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BackgroundMangiferin (MF) was reported to possess anti-inflammatory activity. This investigation tried to probe into the underlying mechanism of MF in osteoarthritis.MethodsATDC5 cells were pretreated with series concentrations of MF (0.1, 1, 5, 10, 15, 20 μM) for 2 h and then were exposed to lipopo...