Knockdown of PGC1α suppresses dysplastic oral keratinocytes proliferation through reprogramming energy metabolism

• Asıl Yazarlar: Yunkun Liu (Yazar), Nengwen Huang (Yazar), Xianghe Qiao (Yazar), Zhiyu Gu (Yazar), Yongzhi Wu (Yazar), Jinjin Li (Yazar), Chengzhou Wu (Yazar), Bo Li (Yazar), Longjiang Li (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Nature Publishing Group, 2023-09-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Abstract Oral potentially malignant disorders (OPMDs) are precursors of oral squamous cell carcinoma (OSCC). Deregulated cellular energy metabolism is a critical hallmark of cancer cells. Peroxisome proliferator-activated receptor-gamma coactivator-1 alpha (PGC1α) plays vital role in mitochondrial e...