Knockdown of PGC1α suppresses dysplastic oral keratinocytes proliferation through reprogramming energy metabolism

• Päätekijät: Yunkun Liu (Tekijä), Nengwen Huang (Tekijä), Xianghe Qiao (Tekijä), Zhiyu Gu (Tekijä), Yongzhi Wu (Tekijä), Jinjin Li (Tekijä), Chengzhou Wu (Tekijä), Bo Li (Tekijä), Longjiang Li (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Nature Publishing Group, 2023-09-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Abstract Oral potentially malignant disorders (OPMDs) are precursors of oral squamous cell carcinoma (OSCC). Deregulated cellular energy metabolism is a critical hallmark of cancer cells. Peroxisome proliferator-activated receptor-gamma coactivator-1 alpha (PGC1α) plays vital role in mitochondrial e...