Food-Derived β-Carboline Alkaloids Ameliorate Lipid Droplet Accumulation in Human Hepatocytes

• Prif Awduron: Dya Fita Dibwe (Awdur), Saki Oba (Awdur), Nire Takeishi (Awdur), Toshihiro Sakurai (Awdur), Takayuki Tsukui (Awdur), Hitoshi Chiba (Awdur), Shu-Ping Hui (Awdur)
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• Cyhoeddwyd: MDPI AG, 2022-05-01T00:00:00Z.
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Lipid droplet accumulation (LDA) in hepatocytes is the initial stage of nonalcoholic fatty liver disease (NAFLD). In the search for natural compounds for the prevention of NAFLD, a series of β-carboline alkaloid derivatives, inspired by flazin and its derivative, newly identified in <i>Crassos...