Food-Derived β-Carboline Alkaloids Ameliorate Lipid Droplet Accumulation in Human Hepatocytes

• Main Authors: Dya Fita Dibwe (Author), Saki Oba (Author), Nire Takeishi (Author), Toshihiro Sakurai (Author), Takayuki Tsukui (Author), Hitoshi Chiba (Author), Shu-Ping Hui (Author)
• Format: Book
• Published: MDPI AG, 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Lipid droplet accumulation (LDA) in hepatocytes is the initial stage of nonalcoholic fatty liver disease (NAFLD). In the search for natural compounds for the prevention of NAFLD, a series of β-carboline alkaloid derivatives, inspired by flazin and its derivative, newly identified in <i>Crassos...