Novel coumarin-6-sulfonamides as apoptotic anti-proliferative agents: synthesis, in vitro biological evaluation, and QSAR studies

• Hoofdauteurs: Ahmed Sabt (Auteur), Omaima M. Abdelhafez (Auteur), Radwan S. El-Haggar (Auteur), Hassan M. F. Madkour (Auteur), Wagdy M. Eldehna (Auteur), Ezz El-Din A. (Auteur), Mohamed A. Abdel-Rahman (Auteur), Laila. A. Rashed (Auteur)
• Formaat: Boek
• Gepubliceerd in: Taylor & Francis Group, 2018-01-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Herein, we report the synthesis of different novel sets of coumarin-6-sulfonamide derivatives bearing different functionalities (4a, b, 8a-d, 11a-d, 13a, b, and 15a-c), and in vitro evaluation of their growth inhibitory activity towards the proliferation of three cancer cell lines; HepG2 (hepatocell...