Strategies to stabilize dalbavancin in aqueous solutions: Section 4-identification of heat degradation products in 2-hydroxypropyl-β-cyclodextrin and divalent metal ion solutions at pH 4.5 and 7.0

• Những tác giả chính: Sardar M. Jakaria (Tác giả), David E. Budil (Tác giả), James Murtagh (Tác giả)
• Định dạng: Sách
• Được phát hành: SpringerOpen, 2023-04-01T00:00:00Z.
• Những chủ đề: article
• Truy cập trực tuyến: Connect to this object online.

Abstract Heat stress studies have been conducted in support of developing a heat-stable liquid solution of dalbavancin. The degradation products that form in heat-stressed buffered dalbavancin solutions have been identified, including the known major degradation product, mannosyl aglycone (MAG), and...