Strategies to stabilize dalbavancin in aqueous solutions: Section 4-identification of heat degradation products in 2-hydroxypropyl-β-cyclodextrin and divalent metal ion solutions at pH 4.5 and 7.0

Abstract Heat stress studies have been conducted in support of developing a heat-stable liquid solution of dalbavancin. The degradation products that form in heat-stressed buffered dalbavancin solutions have been identified, including the known major degradation product, mannosyl aglycone (MAG), and...

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Main Authors: Sardar M. Jakaria (Author), David E. Budil (Author), James Murtagh (Author)
Format: Book
Published: SpringerOpen, 2023-04-01T00:00:00Z.
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3rd Floor Main Library

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