Polyphyllin VI screened from Chonglou by cell membrane immobilized chromatography relieves inflammatory pain by inhibiting inflammation and normalizing the expression of P2X3 purinoceptor

• المؤلفون الرئيسيون: Zhenhui Luo (مؤلف), Tingting Wang (مؤلف), Zhenglang Zhang (مؤلف), Hekun Zeng (مؤلف), Mengqin Yi (مؤلف), Peiyang Li (مؤلف), Jiaqin Pan (مؤلف), Chunyan Zhu (مؤلف), Na Lin (مؤلف), Shangdong Liang (مؤلف), Alexei Verkhratsky (مؤلف), Hong Nie (مؤلف)
• التنسيق: كتاب
• منشور في: Frontiers Media S.A., 2023-02-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Objective: Inflammatory pain is one of the most common diseases in daily life and clinic. In this work, we analysed bioactive components of the traditional Chinese medicine Chonglou and studied mechanisms of their analgesic effects.Material and methods: Molecular docking technology and U373 cells ov...