Click estradiol dimers with novel aromatic bridging units: synthesis and anticancer evaluation
Estradiol dimers (EDs) possess significant anticancer activity by targeting tubulin dynamics. In this study, we synthesised 12 EDs variants via copper-catalysed azide-alkyne cycloaddition (CuAAC) reaction, focusing on structural modifications within the aromatic bridge connecting two estradiol moiet...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Book |
| Published: |
Taylor & Francis Group,
2024-12-01T00:00:00Z.
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| Subjects: | |
| Online Access: | Connect to this object online. |
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