Topotecan inhibits metastasis of non-small cell lung cancer by regulating epithelial-mesenchymal transition

• Главные авторы: Zhen Liu (Автор), Lvqian Guo (Автор), Panpan Yin (Автор), Feng Zhang (Автор), Wenjuan Song (Автор), Junling Gao (Автор), Xinran Li (Автор), Yuou Teng (Автор), Peng Yu (Автор)
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• Опубликовано: Elsevier, 2022-08-01T00:00:00Z.
• Предметы: article
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Lung cancer is a malignant disease with a high mortality rate and a poor prognosis, which is easy to metastasis and recurrence. Topotecan (TPT), an inhibitor of topoisomerase I (Topo I), is mainly used to treat metastatic small cell lung cancer, and it has shown effective treatment for non-small cel...