Topotecan inhibits metastasis of non-small cell lung cancer by regulating epithelial-mesenchymal transition

• Main Authors: Zhen Liu (Author), Lvqian Guo (Author), Panpan Yin (Author), Feng Zhang (Author), Wenjuan Song (Author), Junling Gao (Author), Xinran Li (Author), Yuou Teng (Author), Peng Yu (Author)
• Format: Book
• Published: Elsevier, 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Lung cancer is a malignant disease with a high mortality rate and a poor prognosis, which is easy to metastasis and recurrence. Topotecan (TPT), an inhibitor of topoisomerase I (Topo I), is mainly used to treat metastatic small cell lung cancer, and it has shown effective treatment for non-small cel...