Can circulating cell free DNA be a promising marker in ovarian cancer? - a genome-scale profiling study in a single institution

• Autori principali: Huimei Zhou (Autore), Xueying Zhang (Autore), Qian Liu (Autore), Jiaxin Yang (Autore), Jian Bai (Autore), Min Yin (Autore), Dongyan Cao (Autore), Qingzheng Zhang (Autore), Lu Zheng (Autore)
• Natura: Libro
• Pubblicazione: BMC, 2023-01-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Abstract Background Cell-free DNA (cfDNA) is emerging as a potential biomarker for the detection of ovarian cancer (OC). Recently, we reported a method based upon cfDNA whole-genome sequencing data including the nucleosome distribution (nucleosome footprinting NF), terminal signature sequence (motif...