Can circulating cell free DNA be a promising marker in ovarian cancer? - a genome-scale profiling study in a single institution

• Main Authors: Huimei Zhou (Author), Xueying Zhang (Author), Qian Liu (Author), Jiaxin Yang (Author), Jian Bai (Author), Min Yin (Author), Dongyan Cao (Author), Qingzheng Zhang (Author), Lu Zheng (Author)
• Format: Book
• Published: BMC, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Cell-free DNA (cfDNA) is emerging as a potential biomarker for the detection of ovarian cancer (OC). Recently, we reported a method based upon cfDNA whole-genome sequencing data including the nucleosome distribution (nucleosome footprinting NF), terminal signature sequence (motif...