Exploiting the predictive power of educated spheroids to detect immune-mediated idiosyncratic drug-induced liver injury: the case of troglitazone

Idiosyncratic drug-induced liver injury (iDILI) is a major concern in drug development because its occurrence is unpredictable. Presently, iDILI prediction is a challenge, and cell toxicity is observed only at concentrations that are much higher than the therapeutic doses in preclinical models. Appl...

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Main Authors: Salomé Roux (Author), Sara Cherradi (Author), Hong Tuan Duong (Author)
Format: Book
Published: Frontiers Media S.A., 2024-04-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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