Glutathione Biosynthesis via Activation of the Nuclear Factor E2-Related Factor 2 (Nrf2) - Antioxidant-Response Element (ARE) Pathway Is Essential for Neuroprotective Effects of Sulforaphane and 6-(Methylsulfinyl) Hexyl Isothiocyanate
Oxidative stress plays pivotal roles in aging, neurodegenerative disease, and pathological conditions such as ischemia. We investigated the effect of sulforaphane and 6-(methysulfinyl) hexyl isothiocyanate (6-HITC), a naturally occurring isothiocyanate, on oxidative stress-induced cytotoxicity using...
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Main Authors: | Keita Mizuno (Author), Toshiaki Kume (Author), Chie Muto (Author), Yuki Takada-Takatori (Author), Yasuhiko Izumi (Author), Hachiro Sugimoto (Author), Akinori Akaike (Author) |
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Format: | Book |
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Elsevier,
2011-01-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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