Integration of ATAC-seq and RNA-seq identifies human alpha cell and beta cell signature genes
Objective: Although glucagon-secreting α-cells and insulin-secreting β-cells have opposing functions in regulating plasma glucose levels, the two cell types share a common developmental origin and exhibit overlapping transcriptomes and epigenomes. Notably, destruction of β-cells can stimulate repopu...
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Main Authors: | Amanda M. Ackermann (Author), Zhiping Wang (Author), Jonathan Schug (Author), Ali Naji (Author), Klaus H. Kaestner (Author) |
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Format: | Book |
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Elsevier,
2016-03-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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