Role of TGF-β1/SMAD signaling cascade in the regulation of cyclooxygenase-2 expression in human breast cancer cells
The expression of the SMAD2, SMAD4, SMAD7, and СOX-2 genes and the levels of Smad4, phosphorylated Smad2, and Smad7 proteins were analyzed in the human breast cancer (BC) cell lines MCF-7, BT-474, and ZR-75-1. The SMAD2 and SMAD4 genes were found to suppress COX-2 gene expression in the estrogen rec...
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| Main Authors: | , , , , , |
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| Format: | Book |
| Published: |
ABV-press,
2014-07-01T00:00:00Z.
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| Subjects: | |
| Online Access: | Connect to this object online. |
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