LIT01-196, a Metabolically Stable Apelin-17 Analog, Normalizes Blood Pressure in Hypertensive DOCA-Salt Rats via a NO Synthase-dependent Mechanism

LIT01-196, a Metabolically Stable Apelin-17 Analog, Normalizes Blood Pressure in Hypertensive DOCA-Salt Rats via a NO Synthase-dependent Mechanism

Apelin is a neuro-vasoactive peptide that plays a major role in the control of cardiovascular functions and water balance, but has an in-vivo half-life in the minute range, limiting its therapeutic use. We previously developed LIT01-196, a systemically active metabolically stable apelin-17 analog, p...

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Main Authors: Adrien Flahault (Author), Mathilde Keck (Author), Pierre-Emmanuel G (Author), Lucie Esteoulle (Author), Nadia De Mota (Author), Dominique Bonnet (Author), Catherine Llorens-Cortes (Author)
Format: Book
Published: Frontiers Media S.A., 2021-07-01T00:00:00Z.
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3rd Floor Main Library

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