Highly specific chimeric DNA-RNA-guided genome editing with enhanced CRISPR-Cas12a system

• Autors principals: Hanseop Kim (Autor), Wi-jae Lee (Autor), Chan Hyoung Kim (Autor), Yeounsun Oh (Autor), Lee Wha Gwon (Autor), Hyomin Lee (Autor), Woojeung Song (Autor), Junho K. Hur (Autor), Kyung-Seob Lim (Autor), Kang Jin Jeong (Autor), Ki-Hoan Nam (Autor), Young-Suk Won (Autor), Kyeong-Ryoon Lee (Autor), Youngjeon Lee (Autor), Young-Hyun Kim (Autor), Jae-Won Huh (Autor), Bong-Hyun Jun (Autor), Dong-Seok Lee (Autor), Seung Hwan Lee (Autor)
• Format: Llibre
• Publicat: Elsevier, 2022-06-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

The clustered regularly interspaced short palindromic repeats (CRISPR)-Cas12a system is composed of a Cas12a effector that acts as a DNA-cleaving endonuclease and a crispr RNA (crRNA) that guides the effector to the target DNA. It is considered a key molecule for inducing target-specific gene editin...