Stimulation of soluble guanylate cyclase by vericiguat reduces skeletal muscle atrophy of mice following chemotherapy

• Autori principali: Bo-ang Hu (Autore), Yu-lin Li (Autore), Hai-tao Han (Autore), Bin Lu (Autore), Xu Jia (Autore), Lu Han (Autore), Wei-xuan Ma (Autore), Ping Zhu (Autore), Zhi-hao Wang (Autore), Wei Zhang (Autore), Ming Zhong (Autore), Lei Zhang (Autore)
• Natura: Libro
• Pubblicazione: Frontiers Media S.A., 2023-01-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Background: The chemotherapeutic doxorubicin (DOX) promotes severe skeletal muscle atrophy, which induces skeletal muscle weakness and fatigue. Soluble guanylate cyclase (sGC) contributes to a variety of pathophysiological processes, but whether it is involved in DOX-induced skeletal muscle atrophy...