Suppression of hyperexcitability of trigeminal nociceptive neurons associated with inflammatory hyperalgesia following systemic administration of lutein via inhibition of cyclooxygenase-2 cascade signaling

• Auteurs principaux: Yumiko Syoji (Auteur), Ryota Kobayashi (Auteur), Nako Miyamura (Auteur), Tsukasa Hirohara (Auteur), Yoshiko Kubota (Auteur), Nobuo Uotsu (Auteur), Kei Yui (Auteur), Yoshihito Shimazu (Auteur), Mamoru Takeda (Auteur)
• Format: Livre
• Publié: BMC, 2018-11-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Abstract Introduction Lutein is a dietary constituent known to inhibit inflammation; however, its effect on nociceptive neuron-associated hyperalgesia remains to be determined. The present study therefore investigated under in vivo conditions whether administration of lutein attenuates the inflammat...