Suppression of hyperexcitability of trigeminal nociceptive neurons associated with inflammatory hyperalgesia following systemic administration of lutein via inhibition of cyclooxygenase-2 cascade signaling

• Glavni autori: Yumiko Syoji (Autor), Ryota Kobayashi (Autor), Nako Miyamura (Autor), Tsukasa Hirohara (Autor), Yoshiko Kubota (Autor), Nobuo Uotsu (Autor), Kei Yui (Autor), Yoshihito Shimazu (Autor), Mamoru Takeda (Autor)
• Format: Knjiga
• Izdano: BMC, 2018-11-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

Abstract Introduction Lutein is a dietary constituent known to inhibit inflammation; however, its effect on nociceptive neuron-associated hyperalgesia remains to be determined. The present study therefore investigated under in vivo conditions whether administration of lutein attenuates the inflammat...