Evaluation of near infrared dyes as markers of P-glycoprotein activity in tumors

• Главные авторы: Inessa Semenenko (Автор), Emma Portnoy (Автор), Mohammed AbouKaoud (Автор), Serge Guzy (Автор), Miri Shmuel (Автор), Gal Itzhak (Автор), Sara Eyal (Автор)
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• Опубликовано: Frontiers Media S.A., 2016-11-01T00:00:00Z.
• Предметы: article
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Aim: The multidrug resistance protein 1 (MDR1; P-glycoprotein) has been associated with efflux of chemotherapeutic agents from tumor cells and poor patient prognosis. This study evaluated the feasibility of non-invasive, non-radioactive near infrared (NIR( imaging methodology for detection of MDR1 f...