Evaluation of near infrared dyes as markers of P-glycoprotein activity in tumors

• 主要な著者: Inessa Semenenko (著者), Emma Portnoy (著者), Mohammed AbouKaoud (著者), Serge Guzy (著者), Miri Shmuel (著者), Gal Itzhak (著者), Sara Eyal (著者)
• フォーマット: 図書
• 出版事項: Frontiers Media S.A., 2016-11-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Aim: The multidrug resistance protein 1 (MDR1; P-glycoprotein) has been associated with efflux of chemotherapeutic agents from tumor cells and poor patient prognosis. This study evaluated the feasibility of non-invasive, non-radioactive near infrared (NIR( imaging methodology for detection of MDR1 f...