Autocrine EGF and TGF‐α promote primary and acquired resistance to ALK/c‐Met kinase inhibitors in non‐small‐cell lung cancer

• मुख्य लेखकों: Yueqin Wang (लेखक), Yu Zhang (लेखक), Ruiying Chen (लेखक), Xin Tian (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Wiley, 2023-02-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Abstract Drug resistance severely limits the clinical therapeutic value of molecularly targeted drugs. Growth factors gain a tremendous amount of focus due to the ability to promote drug resistance in non‐small‐cell lung cancer (NSCLC). However, whether tumor cells themselves can mediate drug resist...