Autocrine EGF and TGF‐α promote primary and acquired resistance to ALK/c‐Met kinase inhibitors in non‐small‐cell lung cancer

• Päätekijät: Yueqin Wang (Tekijä), Yu Zhang (Tekijä), Ruiying Chen (Tekijä), Xin Tian (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Wiley, 2023-02-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Abstract Drug resistance severely limits the clinical therapeutic value of molecularly targeted drugs. Growth factors gain a tremendous amount of focus due to the ability to promote drug resistance in non‐small‐cell lung cancer (NSCLC). However, whether tumor cells themselves can mediate drug resist...