Autocrine EGF and TGF‐α promote primary and acquired resistance to ALK/c‐Met kinase inhibitors in non‐small‐cell lung cancer

Abstract Drug resistance severely limits the clinical therapeutic value of molecularly targeted drugs. Growth factors gain a tremendous amount of focus due to the ability to promote drug resistance in non‐small‐cell lung cancer (NSCLC). However, whether tumor cells themselves can mediate drug resist...

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Autores principales: Yueqin Wang (Autor), Yu Zhang (Autor), Ruiying Chen (Autor), Xin Tian (Autor)
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Publicado: Wiley, 2023-02-01T00:00:00Z.
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