Peptide-RNA complexation-induced fluorescence "turn on" displacement assay for the recognition of small ligands targeting HIV-1 RNA

• मुख्य लेखकों: Liang Qi (लेखक), Jiayun Zhang (लेखक), Ying Gao (लेखक), Pin Gong (लेखक), Chengyuan Liang (लेखक), Yao Su (लेखक), Qiao Zeng (लेखक), Yafeng Zhang (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Elsevier, 2022-12-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

The regulator of expression of virion (Rev) protein binds specifically to the Rev-responsive element (RRE) RNA in order to regulate the expression of the human immunodeficiency virus (HIV)-1 genes. Fluorescence indicator displacement assays have been used to identify ligands that can inhibit the Rev...