Proteomics analysis reveals novel insights into the mechanism of hepatotoxicity induced by Tripterygium wilfordii multiglycoside in mice

• Main Authors: Yingying Miao (Author), Qin Zhang (Author), Zihang Yuan (Author), Jie Wang (Author), Yunxia Xu (Author), Yuanyuan Chai (Author), Min Du (Author), Qinwei Yu (Author), Luyong Zhang (Author), Zhenzhou Jiang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Tripterygium wilfordii multiglycoside (GTW), extracted and purified from the peeled roots of T. wilfordii Hook.f. (TwHF), is a well-known traditional Chinese medicine and applied to various autoimmune diseases clinically. However, it has been reported to cause severe liver injury. At present, the me...