Proteomics analysis reveals novel insights into the mechanism of hepatotoxicity induced by Tripterygium wilfordii multiglycoside in mice

• Egile Nagusiak: Yingying Miao (Egilea), Qin Zhang (Egilea), Zihang Yuan (Egilea), Jie Wang (Egilea), Yunxia Xu (Egilea), Yuanyuan Chai (Egilea), Min Du (Egilea), Qinwei Yu (Egilea), Luyong Zhang (Egilea), Zhenzhou Jiang (Egilea)
• Formatua: Liburua
• Argitaratua: Frontiers Media S.A., 2022-11-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Tripterygium wilfordii multiglycoside (GTW), extracted and purified from the peeled roots of T. wilfordii Hook.f. (TwHF), is a well-known traditional Chinese medicine and applied to various autoimmune diseases clinically. However, it has been reported to cause severe liver injury. At present, the me...