The Effect of Tween 20, 60, and 80 on Dissolution Behavior of Sprionolactone in Solid Dispersions Prepared by PEG 6000

• मुख्य लेखकों: Jafar Akbari (लेखक), Majd Saeedi (लेखक), Katayoun Morteza-Semnani (लेखक), Hamid Reza Kelidari (लेखक), Farshad Sadegh Moghanlou (लेखक), Gity Zareh (लेखक), Sohrab Rostamkolaei (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Tabriz University of Medical Sciences, 2015-09-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Purpose: Solid dispersions have been efficient in improving the dissolution rate and bioavailability of hydrophobic drugs. The aim of the present study was enhancement of the dissolution profile of Spironolactone using solid dispersion. Methods: Spironolactone solid dispersions (1:1, 1:2 and 2:1 dru...