A Four-Point Screening Method for Assessing Molecular Mechanism of Action (MMOA) Identifies Tideglusib as a Time-Dependent Inhibitor of Trypanosoma brucei GSK3β.
New therapeutics are needed for neglected tropical diseases including Human African trypanosomiasis (HAT), a progressive and fatal disease caused by the protozoan parasites Trypanosoma brucei gambiense and T. b. rhodesiense. There is a need for simple, efficient, cost effective methods to identify n...
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| Main Authors: | , , , , , , , |
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| Format: | Book |
| Published: |
Public Library of Science (PLoS),
2016-03-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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