Host regulation of liver fibroproliferative pathology during experimental schistosomiasis via interleukin-4 receptor alpha.

• 主要な著者: Justin Komguep Nono (著者), Hlumani Ndlovu (著者), Nada Abdel Aziz (著者), Thabo Mpotje (著者), Lerato Hlaka (著者), Frank Brombacher (著者)
• フォーマット: 図書
• 出版事項: Public Library of Science (PLoS), 2017-08-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Interleukin-4 receptor (IL-4Rα) is critical for the initiation of type-2 immune responses and implicated in the pathogenesis of experimental schistosomiasis. IL-4Rα mediated type-2 responses are critical for the control of pathology during acute schistosomiasis. However, type-2 responses tightly ass...