AIRE deficiency, from preclinical models to human APECED disease

• Asıl Yazarlar: Marine Besnard (Yazar), Francine Padonou (Yazar), Nathan Provin (Yazar), Matthieu Giraud (Yazar), Carole Guillonneau (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: The Company of Biologists, 2021-02-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy (APECED) is a rare life-threatening autoimmune disease that attacks multiple organs and has its onset in childhood. It is an inherited condition caused by a variety of mutations in the autoimmune regulator (AIRE) gene that encodes a prot...