HLA Class I-T cell epitopes from trans-sialidase proteins reveal functionally distinct subsets of CD8+ T cells in chronic Chagas disease.

• 主要な著者: María G Alvarez (著者), Miriam Postan (著者), D Brent Weatherly (著者), María C Albareda (著者), John Sidney (著者), Alessandro Sette (著者), Carina Olivera (著者), Alejandro H Armenti (著者), Rick L Tarleton (著者), Susana A Laucella (著者)
• フォーマット: 図書
• 出版事項: Public Library of Science (PLoS), 2008-01-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

BACKGROUND:Previously, we identified a set of HLA-A020.1-restricted trans-sialidase peptides as targets of CD8+ T cell responses in HLA-A0201+ individuals chronically infected by T. cruzi. METHODS AND FINDINGS:Herein, we report the identification of peptides encoded by the same trans-sialidase gene...