Preparation, characterization, and in vitro/vivo evaluation of polymer-assisting formulation of atorvastatin calcium based on solid dispersion technique

Due to low solubility and bioavailability, atorvastatin calcium is confronted with challenge in conceiving appropriate formulation. Solid dispersion of atorvastatin calcium was prepared through the solvent evaporation method, with Poloxamer 188 as hydrophilic carriers. This formulation was then char...

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Main Authors: Wenxiang Dong (Author), Xitong Su (Author), Meng Xu (Author), Mingming Hu (Author), Yinghua Sun (Author), Peng Zhang (Author)
Format: Book
Published: Elsevier, 2018-11-01T00:00:00Z.
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3rd Floor Main Library

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