Comparison of Two Mice Strains, A/J and C57BL/6, in Caspase-1 Activity and IL-1β Secretion of Macrophage to Mycobacterium leprae Infection

• Päätekijät: Tae Jin Kang (Tekijä), Geum Seon Lee (Tekijä), Se Kon Kim (Tekijä), Song Hou Jin (Tekijä), Gue Tae Chae (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Hindawi Limited, 2010-01-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

A/J mice were found to have amino acid differences in Naip5, one of the NOD-like receptors (NLRs) involved in the cytosolic recognition of pathogen-associated molecular patterns and one of the adaptor proteins for caspase-1 activation. This defect was associated with a susceptibility to Legionella i...