UPLC-MS/MS method for simultaneously determining nucleosides and methyl-nucleosides in liver mRNA of Epimedin C-induced liver injury mouse model

Abstract Background Epimedin C, one of the main active ingredients of Epimedium, has been reported to have potential hepatotoxicity. However, the mechanism of Epimedin C-induced liver injury has not been studied. mRNA methylation, mainly including N6-methyladenosine and N5-methylcytidine, is implica...

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Main Authors: Zhizhen Song (Author), Zeyun Li (Author), Xueqian Wen (Author), Ruijuan Liu (Author), Xin Tian (Author)
Format: Book
Published: BMC, 2021-09-01T00:00:00Z.
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