Let-7i-5p Mediates the Therapeutic Effects of Exosomes from Human Placenta Choriodecidual Membrane-Derived Mesenchymal Stem Cells on Mitigating Endotoxin-Induced Mortality and Liver Injury in High-Fat Diet-Induced Obese Mice

Obesity complicates sepsis and increases the mortality of sepsis. We examined the effects of exosomes (from human placenta choriodecidual membrane-derived mesenchymal stem cells, pcMSCs) on preventing sepsis in obesity and the mitigating role of hsa-let-7i-5p microRNA. Obese mice (adult male C57BL/6...

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Main Authors: Chao-Yuan Chang (Author), Kung-Yen Chen (Author), Hung-Jen Shih (Author), Milton Chiang (Author), I-Tao Huang (Author), Yen-Hua Huang (Author), Chun-Jen Huang (Author)
Format: Book
Published: MDPI AG, 2021-12-01T00:00:00Z.
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