KLF 15 Works as an Early Anti-Fibrotic Transcriptional Regulator in Ang II-Induced Renal Fibrosis via Down-Regulation of CTGF Expression

• Main Authors: Xiangchen Gu (Author), Dechao Xu (Author), Lili Fu (Author), Yi Wang (Author), Changlin Mei (Author), Xiang Gao (Author)
• 格式: 图书
• 出版: Karger Publishers, 2017-11-01T00:00:00Z.
• 主题: article
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Background/Aims: Angiotensin II (Ang II) has been regarded as an important profibrogenic cytokine in renal fibrosis. Krüppel-like factor 15 (KLF15) has been identified as an important negative transcription factor in renal fibrosis. However, little is known about the role of KLF15 in Ang II-induced...