KLF 15 Works as an Early Anti-Fibrotic Transcriptional Regulator in Ang II-Induced Renal Fibrosis via Down-Regulation of CTGF Expression

• Egile Nagusiak: Xiangchen Gu (Egilea), Dechao Xu (Egilea), Lili Fu (Egilea), Yi Wang (Egilea), Changlin Mei (Egilea), Xiang Gao (Egilea)
• Formatua: Liburua
• Argitaratua: Karger Publishers, 2017-11-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Background/Aims: Angiotensin II (Ang II) has been regarded as an important profibrogenic cytokine in renal fibrosis. Krüppel-like factor 15 (KLF15) has been identified as an important negative transcription factor in renal fibrosis. However, little is known about the role of KLF15 in Ang II-induced...