An accomplice more than a mere victim: The impact of β-cell ER stress on type 1 diabetes pathogenesis
Background: Pancreatic β-cells are the insulin factory of an organism with a mission to regulate glucose homeostasis in the body. Due to their high secretory activity, β-cells rely on a functional and intact endoplasmic reticulum (ER). Perturbations to ER homeostasis and unmitigated stress lead to β...
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Format: | Book |
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Elsevier,
2021-12-01T00:00:00Z.
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A1234.567 |
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