Development of Non-Ethoxypropanoic Acid Type Cryptochrome Inhibitors with Circadian Molecular Clock-Enhancing Activity by Bioisosteric Replacement

• Autori principali: Yong Uk Jeong (Autore), Hyo-Eon Jin (Autore), Hye Young Lim (Autore), Goyeong Choi (Autore), Hansol Joo (Autore), Bohun Kang (Autore), Ga-Hyun Lee (Autore), Kwang-Hyeon Liu (Autore), Han-Joo Maeng (Autore), Sooyoung Chung (Autore), Gi Hoon Son (Autore), Jong-Wha Jung (Autore)
• Natura: Libro
• Pubblicazione: MDPI AG, 2021-05-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Circadian dysfunction is closely associated with an increased risk of various diseases. Considering that molecular clock machinery serves as an intrinsic time-keeping system underlying the circadian rhythm of biological processes, the modulation of the molecular clock machinery is an attractive ther...