DdCBE mediates efficient and inheritable modifications in mouse mitochondrial genome
Critical mutations of mitochondrial DNA (mtDNA) generally lead to maternally inheritable diseases that affect multiple organs and systems; however, it was difficult to alter mtDNA in mammalian cells to intervene in or cure mitochondrial disorders. Recently, the discovery of DddA-derived cytosine bas...
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| Main Authors: | , , , , , , , , , , , , , , |
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| Format: | Book |
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Elsevier,
2022-03-01T00:00:00Z.
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