Exosome miR-155 Derived from Gastric Carcinoma Promotes Angiogenesis by Targeting the c-MYB/VEGF Axis of Endothelial Cells

• Главные авторы: Ting Deng (Автор), Haiyang Zhang (Автор), Haiou Yang (Автор), Huiya Wang (Автор), Ming Bai (Автор), Wu Sun (Автор), Xinyi Wang (Автор), Yiran Si (Автор), Tao Ning (Автор), Le Zhang (Автор), Hongli Li (Автор), Shaohua Ge (Автор), Rui Liu (Автор), Dan Lin (Автор), Shuang Li (Автор), Guoguang Ying (Автор), Yi Ba (Автор)
• Формат: ‌
• Опубликовано: Elsevier, 2020-03-01T00:00:00Z.
• Предметы: article
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Exosomes, membranous nanovesicles, naturally carry proteins, mRNAs, and microRNAs (miRNAs) and play important roles in tumor pathogenesis. Here we showed that gastric cancer (GC) cell-derived exosomes can function as vehicles to deliver miR-155 to promote angiogenesis in GC. In this study, we first...