Exosome miR-155 Derived from Gastric Carcinoma Promotes Angiogenesis by Targeting the c-MYB/VEGF Axis of Endothelial Cells

• Main Authors: Ting Deng (Author), Haiyang Zhang (Author), Haiou Yang (Author), Huiya Wang (Author), Ming Bai (Author), Wu Sun (Author), Xinyi Wang (Author), Yiran Si (Author), Tao Ning (Author), Le Zhang (Author), Hongli Li (Author), Shaohua Ge (Author), Rui Liu (Author), Dan Lin (Author), Shuang Li (Author), Guoguang Ying (Author), Yi Ba (Author)
• Format: Book
• Published: Elsevier, 2020-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Exosomes, membranous nanovesicles, naturally carry proteins, mRNAs, and microRNAs (miRNAs) and play important roles in tumor pathogenesis. Here we showed that gastric cancer (GC) cell-derived exosomes can function as vehicles to deliver miR-155 to promote angiogenesis in GC. In this study, we first...