FTO is necessary for the induction of leptin resistance by high-fat feeding

• Главные авторы: Y.C. Loraine Tung (Автор), Pawan Gulati (Автор), Che-Hsiung Liu (Автор), Debra Rimmington (Автор), Rowena Dennis (Автор), Marcella Ma (Автор), Vladimir Saudek (Автор), Stephen O'Rahilly (Автор), Anthony P. Coll (Автор), Giles S.H. Yeo (Автор)
• Формат: ‌
• Опубликовано: Elsevier, 2015-04-01T00:00:00Z.
• Предметы: article
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Objective: Loss of function FTO mutations significantly impact body composition in humans and mice, with Fto-deficient mice reported to resist the development of obesity in response to a high-fat diet (HFD). We aimed to further explore the interactions between FTO and HFD and determine if FTO can in...