Estradiol inhibits phosphorylation of JAK/STAT, PI3K/AKT and expression of IL-17A in mouse mononuclear cells treated with IL-36β

• Главные авторы: Shuang LIU (Автор), Shanshan YANG (Автор), Chunchan ZHENG (Автор), Sujun LUO (Автор), Na WEI (Автор), Sirui LI (Автор), Jianqiang SHI (Автор), Rongyi CHEN (Автор)
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• Опубликовано: editoiral office of Journal of Diagnosis and Therapy on Dermato-venereology, 2023-02-01T00:00:00Z.
• Предметы: article
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Objective To investigate the effects of β-estradiol (E2) on the phosphorylation of JAK/STAT, PI3K/AKT signaling pathways and the expression of IL-17A in mouse spleen mononuclear cells treated with IL-36β. Methods The spleens were isolated from female SPF C57BL/6 mice aged 6-8 weeks. The mononuclear...