Estradiol inhibits phosphorylation of JAK/STAT, PI3K/AKT and expression of IL-17A in mouse mononuclear cells treated with IL-36β

• Glavni autori: Shuang LIU (Autor), Shanshan YANG (Autor), Chunchan ZHENG (Autor), Sujun LUO (Autor), Na WEI (Autor), Sirui LI (Autor), Jianqiang SHI (Autor), Rongyi CHEN (Autor)
• Format: Knjiga
• Izdano: editoiral office of Journal of Diagnosis and Therapy on Dermato-venereology, 2023-02-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

Objective To investigate the effects of β-estradiol (E2) on the phosphorylation of JAK/STAT, PI3K/AKT signaling pathways and the expression of IL-17A in mouse spleen mononuclear cells treated with IL-36β. Methods The spleens were isolated from female SPF C57BL/6 mice aged 6-8 weeks. The mononuclear...